Watch Closely (1)lumefantrine will lower the level or impact of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. For clients acquiring exemestane which has a potent CYP3A4 inducer the suggested dose of exemestane is 50 mg day by day after a food.
dexamethasone will lower the level or impact of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
erythromycin lactobionate will raise the degree or influence of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
In the event you skip a dose of exemestane, consider it as soon as you keep in mind if it is in just twelve hrs with the missed dose. If it has been more than twelve hrs, skip the missed dose and consider your future dose at the standard time.
Discuss with your health practitioner or nurse about successful contraception. They can let you know how long to carry on utilizing contraception Once you prevent getting exemestane.
Exemestane has become Employed in doping to lift luteinizing hormone (LH) and follicle stimulating hormone (FSH) degrees, which subsequently enhances the ratio of male more than female sexual hormones and so improves general performance. The drug also counteracts gynecomastia in addition to Excess fat and water retention adhering to abnormal aromatase output on account of testosterone doping.
You may also knowledge Negative effects attributable to other solutions or individual circumstance, such as the menopause. If you are worried about any long term Negative effects right after stopping exemestane, talk to your therapy team or GP.
estropipate decreases outcomes of exemestane by pharmacodynamic antagonism. Use Warning/Observe. Estrogens or estrogen-containing products and solutions, which include mixed oral contraceptives, really should not be presented concomitantly with exemestane; these medicine could interfere Together with the pharmacologic action and efficacy of exemestane.
Exemestane can reduce the number of white blood cells. This may improve the possibility of acquiring an an infection.
In case you miss out on a dose, acquire it when you keep in mind. If it is near the time of the next dose, skip the missed dose. Just take your next dose for the normal time. Do not double the dose to catch up.
Tell your doctor about many of the medicines you take, such as prescription and around-the-counter medicines, nutritional vitamins and herbal nutritional supplements. Primarily tell your physician if you're taking medicines that include estrogen, together with other hormone substitute therapy or start Regulate tablets or patches.
A generic drug is an actual copy with the Energetic drug in a very brand name-name medication. The generic is thought to be equally as Secure and powerful as the original drug. Generics also usually Price tag fewer than brand name-identify medicine.
Exemestane can minimize bone mineral density, which may enhance your danger of developing osteoporosis. Check with your health practitioner about your particular person hazard of bone loss.
estrogens esterified more info decreases outcomes of exemestane by pharmacodynamic antagonism. Use Caution/Monitor. Estrogens or estrogen-made up of products and solutions, together with merged oral contraceptives, shouldn't be presented concomitantly with exemestane; these prescription drugs could interfere Along with the pharmacologic action and efficacy of exemestane.